Description
CP-673451 is a potent small-molecule inhibitor of platelet-derived growth factor receptors (PDGFR-α and PDGFR-β), key regulators of signaling pathways involved in cell proliferation, migration, and angiogenesis. By selectively blocking PDGFR activity, CP-673451 effectively suppresses downstream signaling, making it a valuable tool for studying receptor tyrosine kinase function.
CP-673451 is widely used in cell-based assays to investigate PDGFR-driven processes, including tumor growth, vascular development, and fibrotic responses. Its selective mechanism enables precise pathway modulation, supporting both mechanistic studies and drug discovery applications.
Key Features:
- Potent inhibitor of PDGFR-α and PDGFR-β
- Suppresses PDGFR-mediated signaling pathways
- High activity in cell-based assays
- Useful for cancer, angiogenesis, and fibrosis research
Applications:
- PDGFR signaling pathway studies
- Cancer biology and tumor progression research
- Angiogenesis and vascular biology
- Fibrosis research and target validation
Formulation & Storage:
- Typically supplied as a solid powder
- Soluble in DMSO
- Store at -20°C, desiccated, and protected from light
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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