Description
BRD0705 is a potent and highly selective small-molecule inhibitor of glycogen synthase kinase-3 alpha (GSK-3α), with minimal activity against the closely related GSK-3β isoform. By selectively targeting GSK-3α, BRD0705 enables precise investigation of isoform-specific functions in cellular signaling, metabolism, and disease biology.
BRD0705 has been widely used in studies of neurodevelopmental disorders, cancer, and metabolic regulation, where GSK-3α plays a distinct role. Its high selectivity makes it a valuable tool for dissecting GSK-3 isoform biology and for advancing targeted therapeutic research.
Key Features:
- Highly selective inhibitor of GSK-3α over GSK-3β
- Enables isoform-specific pathway studies
- Active in cell-based assays
- Useful in neuroscience, oncology, and metabolic research
Applications:
- GSK-3 signaling pathway studies
- Neurodevelopmental and neurological disorder research
- Cancer and cell proliferation studies
- Target validation and drug discovery
Formulation & Storage:
- Supplied as a solid powder
- Soluble in DMSO
- Store at -20°C, desiccated, and protected from light
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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