Gene edited chicken egg can be used for the safe and cost-effective therapeutic protein production. Past methods for constructing such egg bioreactors are difficult and time consuming. In this project ATGC will work with University of Southern California to develop a embryonic stem cell based method for the fast egg bioreactor construction. The method will first be demonstrated by producing recombinant human GalA, which is the current treatment for Fabry disease affecting 1 in 40,000 to 117,000 live births. For details of the technology please search Project Number 1R41GM146516 in NIH RePORTER.
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